Long-term effects of weight-reducing interventions in hypertensive patients: systematic review and meta-analysis.
نویسندگان
چکیده
Weight loss is recommended in all major guidelines for antihypertensive therapy. We searched for randomized controlled trials investigating the effects of weight-reducing diets, pharmacologic substances, and invasive interventions for weight reduction on patient-relevant end points and blood pressure (BP) in patients with essential hypertension. No information on the effects on patient-relevant end points was available. Patients assigned to weight loss diets, orlistat, or sibutramine reduced their body weight more effectively than did patients in the usual care/placebo groups. Reduction of BP was higher in patients treated with weight loss diets (systolic BP [SBP]: weighted mean difference [WMD], -6.3 mm Hg; diastolic BP [DBP]: WMD, -3.4 mm Hg) or orlistat (SBP: WMD, -2.5 mm Hg; DBP: WMD, -2.0 mm Hg). Systolic BP increased with sibutramine treatment (WMD, 3.2 mm Hg). In patients with essential hypertension, therapy with a weight loss diet or orlistat resulted in reductions in body weight and BP. Although sibutramine treatment reduced body weight, it did not lower BP.
منابع مشابه
The Effect of Lifestyle Intervention on Pregnancy and Birth Outcomes on Obese Infertile Women: A Systematic Review and Meta-Analysis
Background: Obesity has been associated to negative effects on natural fertility and a worse prognosis when assisted reproduction techniques are performed. Patients attending for fertility treatments are often advised to optimize their weights to improve outcomes. There are doubts about how effective are weight-loss interventions for improving fertility in women who are overweight or obese. Mat...
متن کاملMindfulness-Based Interventions for parents of slow-paced people: A Systematic review and meta-analysis
Objective: Mindful-based interventions have been the focus of attention among the third wave of cognitive-behavioral followers, in recent years. A variety of interventional techniques such as acceptance, emotional control, cognitive restructuring are increasingly incorporated into the interventional framework directed to help slow-paced population parents and caregivers. Method: The present stu...
متن کاملA Systematic Review and Meta-Analysis of Randomized Controlled Trials Comparing the Safety of Dapagliflozin in Type 1 Diabetes Patients
Background and Purpose: The dapagliflozin’s safety profile in insulin-treated adult type-1 diabetes mellites (T1DM) patients remains poorly explored. Therefore, this systematic review and meta-analysis compared the risk of all-cause side effects, study discontinuation of participants due to side effects, urinary tract infection (UTI), diabetic ketoacidosis, and hypoglycemia between dapagliflozi...
متن کاملPsychological interventions in chronic low back pain: A systematic review study
Background and Aim: Chronic low back pain (CLBP) is one of the most common musculoskeletal disorders that can have psychological consequences for these patients. The aim of this study was to review psychological interventions for people with chronic low back pain. Methods and Materials: This survey was a systematic review conducted from January 2010 to December 2020. The keywords included ...
متن کاملThe Impact of Different Modes of Exercise Training on Irisin: A Systematic Review and Meta-Analysis Research
Background & Objective: Irisin is considered as a candidate to treat obesity and metabolic diseases. Therefore, the aim of this study was a systematic review and meta-analysis to define the effective modes of exercise on irisin concentration in adults. Materials & Methods: Google Scholar, PubMed, Medline, Scopus, Science Direct, and references lists of articles were searched until April ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Archives of internal medicine
دوره 168 6 شماره
صفحات -
تاریخ انتشار 2008